Chemistry Capabilities
You are here: PharmaBlock USA » About Us-PharmaBlock USA » Chemistry Capabilities
Chemistry Capabilities
Chemistry Capabilities
  • — Precise route selection & phase-appropriate process and analytical development
  • — Process development, optimization and rapid scale-up of building blocks, key intermediates, RSMs and APIs.
  • — Expertise in DoE, Quality by Design (QbD) approach to Process Development
  • — Critical process parameters (CPP) and critical quality attributes (CQA) evaluation
  • — Reaction modeling/simulation, DFT calculations
  • — Crystallization development, salt screen/selection and polymorph control
  • — Continuous flow processing up to kilo scale
  • — Continuous micropacked bed reactors for reductions and debenzylations
  • — Enzymatic reactions
  • — Early phase toxicology batches
  • — GLP tox batches, early phase clinical batches (cGMP) 
Services
— Method Development & Validation
— ICH Stability Studies
— Impurity isolation, identification and structure elucidation
— Reference Standard Certification
— Chiral & achiral separations via GC, HPLC
Analytical / QC
— Analytical Method Development/Validation/transfer
—​​​​​​​GMP release testing
—​​​​​​​Residual Solvents testing
—​​​​​​​Compendial Method Verification/Testing
—​​​​​​​Impurity isolation and identification by Prep-LC,LC/MS, NMR
—​​​​​​​Stability Chamber
    · ICH stability storage and testing (25°C/60% RH; 30°C/65% RH;
      40°C/75% RH; 2-8 °C)
   · Photostability study
   · 24/7 alarms: email/online system

QUICK LINKS

SERVICES & SOLUTIONS

Call Now For Service!

1-877 878 5226
1-267 649 7271
777 Schwab Rd,Unit D Hatfield,
PA 19440,USA
Copyright 2022 PharmaBlock (USA), Inc. Support By Leadong. Sitemap.